The roles of vitamin C in skin health
Comprehensive review of vitamin C's cofactor, antioxidant, and photoprotective roles in both the epidermis and dermis.
The collagen cofactor. The same L-ascorbic acid you're spending $80 on in a serum — except this one gets to your skin from the inside.
Why it's in Glowbite
* These statements have not been evaluated by the FDA.
Mechanism
Ascorbic acid is an essential cofactor for prolyl- and lysyl-hydroxylase, the enzymes that hydroxylate collagen so it can form its triple helix. It also quenches aqueous-phase free radicals and regenerates oxidized vitamin E at membrane surfaces.*
Why this dose
100 mg is several times the RDA (90 mg for adult men / 75 mg for women) and within the routine range of skin-focused supplements. Saturation of plasma ascorbate occurs around 400 mg/day; doses above this are progressively excreted.
Representative studies
Comprehensive review of vitamin C's cofactor, antioxidant, and photoprotective roles in both the epidermis and dermis.
Interactions & cautions
Very high doses (2000 mg+) may cause GI upset and, rarely, kidney stones in predisposed individuals. Patients with hemochromatosis should note that vitamin C enhances iron absorption.
See the full safety page for contraindications across all seven actives.
Pairs with
Vitamin C does part of the job. These are the other actives in Glowbite that work on adjacent pathways.
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