Carotenoids and carotenoid-rich foods in human health
Rao A.V., Rao L.G. · Pharmacological Research · 2007
Review article covering mechanistic and epidemiological evidence for carotenoid intake and photo-protective endpoints.
iii.
Vitamin A
Orange-yellow plant pigment converted to retinol on demand
The vitamin that keeps skin cells cycling through properly — think turnover, texture, the glow that shows up when your skin is actually doing its job.
Dose per gummy
8000 mcg RAE
833% DV
Provitamin beta carotene
Why it's in Glowbite
What it does
for you.
- i.Supports skin cell turnover and a fresh, even complexion*
- ii.Beta carotene form is self-regulating — the body converts as needed*
- iii.Contributes to normal vision and immune function*
- iv.Fat-soluble — take with a meal for best absorption
* These statements have not been evaluated by the FDA.
Mechanism
How it actually
works.
Dietary beta carotene is cleaved by the BCO1 enzyme into retinal and then retinol, which binds to retinoic acid receptors to regulate epidermal differentiation. Because the conversion is regulated, beta carotene doesn't cause hypervitaminosis-A in the way preformed retinol can.*
Why this dose
The dose
rationale.
8000 mcg RAE via beta carotene is within the range used in commercial skin-focused supplements. Unlike preformed retinol, beta carotene has no established UL from dietary sources; however, smokers and heavy drinkers should speak with their doctor before supplementing any beta carotene.
Representative studies
The
receipts.
Beta-carotene and other carotenoids as antioxidants
Sies H., Stahl W. · Journal of the American College of Nutrition · 1995
Classic mechanistic paper describing the antioxidant activity of beta carotene and related pigments in biological membranes.
Interactions & cautions
Who should check with
a doctor first.
Not recommended during pregnancy in high doses; beta carotene is generally preferable to retinol but check with your OB. Current smokers should speak with their doctor — some high-dose beta carotene trials in heavy-smoker cohorts raised safety concerns.
See the full safety page for contraindications across all seven actives.
Pairs with
Actives that work
alongside.
Vitamin A does part of the job. These are the other actives in Glowbite that work on adjacent pathways.
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