Vitamin B3 (Niacinamide)

The non-flushing form of vitamin B3

The same niacinamide that's in the serum on your bathroom shelf — working on the other side of the skin.

Dose per gummy

50 mg

313% DV

USP-grade niacinamide

Why it's in Glowbite

What it does
for you.

i.Supports a smooth, even-toned complexion*
ii.Non-flushing form of B3 (unlike nicotinic acid)*
iii.Complements topical niacinamide by working from inside*
iv.Supports skin barrier lipid synthesis*

* These statements have not been evaluated by the FDA.

Mechanism

How it actually
works.

Niacinamide is a precursor to NAD+ and NADP+, cofactors required by hundreds of cellular reactions including those that power keratinocyte metabolism, lipid synthesis, and DNA repair. Topical and oral niacinamide have independently been associated with improvements in skin barrier and evenness.*

Why this dose

The dose
rationale.

50 mg is well below the 500 mg/day used in dermatology research on actinic-keratosis endpoints. There is no reported UL for niacinamide below several hundred mg; flushing associated with niacin does not apply to the niacinamide form.

Representative studies

The
receipts.

Nicotinamide and the skin

Rolfe H.M. · Australasian Journal of Dermatology · 2014

Review of oral and topical niacinamide evidence across photoaging, rosacea, barrier function, and non-melanoma skin cancer endpoints.

A Phase 3 Randomized Trial of Nicotinamide for Skin-Cancer Chemoprevention

Chen A.C. et al. · New England Journal of Medicine · 2015

High-dose oral nicotinamide (500 mg twice daily) reduced incidence of new non-melanoma skin cancers in high-risk adults — not a Glowbite claim, but foundational safety/efficacy evidence for oral niacinamide.

Interactions & cautions

Who should check with
a doctor first.

Large doses (>3 g/day) of niacinamide have been rarely associated with liver enzyme elevations in sensitive individuals. At 50 mg this is not a concern for most adults.

See the full safety page for contraindications across all seven actives.

Pairs with